10U.S. Route 50 – Nevada (The Loneliest Road in America)
Known famously as “The Loneliest Road in America,” Nevada’s U.S. Route 50 spans about 400 miles across the state. It traverses expansive deserts, remote basins, and ghost towns, creating an experience that feels like stepping into another world. With very few services along the way, travelers are advised to fuel up and bring supplies. Stops like Austin and Ely add a touch of old mining history, but the wide-open stretches are what give this road its solitary charm.